Publications

1. Heden TD, Neufer PD, Funai K. Looking beyond structure: membrane phospholipids of skeletal muscle mitochondria. Trends in Endocrinology & Metabolism. 27(8):553-562, 2016.

2. Funai K, Lodhi IJ, Spears LD, Yin L, Song H, Klein S, Semenkovich CF. Skeletal muscle phosphilipid metabolism regulates insulin sensitivity and contractile function. Diabetes. 65(2):358-370, 2016.

3. Paran CW, Zou K, Ferrara PJ, Song H, Turk J, Funai K. Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy. BBA - Molecular and Cell Biology of Lipids. 1852(12):1530-1538, 2015..

4. Paran CW, Verkerke ARP, Heden TD, Park S, Zou K, Lawson HA, Song H, Turk J, Houmard JA, Funai K. Reduced efficiency of sarcolipin-dependent respiration in myocytes from humans with severe obesity. Obesity. 23(7): 1440-1449, 2015.

5. Oh J, Riek AE, Darwech I, Funai K, Shao J, Chin K, Sierra OL, Carmeliet G, Ostlund RE, Bernal-Mizrachi C. Deletion of macrophage vitamin D receptor promotes insulin resistance and monocyte cholesterol transport to accelerate atherosclerosis in mice. Cell Reports. 10(11): 1872-1886, 2015.

6. Ridaura VK, Faith JJ, Rey FE, Cheng J, Duncan AE, Kau AL, Griffin NW, Lombard V, Henrissat B, Bain JR, Muehlbauer MJ, Ilkayeva O, Semenkovich CF, Funai K, Hayashi DK, Lyle BJ, Martini MC, Ursell LK, Clemente JC, Van Treuren W, Walters WA, Knight R, Newgard CB, Heath AC, Gordon JI. Cultured gut bacterial consortia from twins discordant for obesity modulate adiposity and metabolic phenotypes in gnotobiotic mice. Science. 341(6150): 1241214, 2013.

7. Funai K, Song H, Yin L, Lodhi IJ, Wei X, Yoshino, J, Coleman T, Semenkovich CF. Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling. J Clin Invest. 123(3):1229-1240, 2013.

8. Jensen-Urstad APL, Song H, Lodhi IJ, Funai K, Yin L, Coleman T, Semenkovich CF. Nutrient-dependent phosphorylation channels lipid synthesis to regulate PPARα. J Lipid Res. 54(7):1848-1859, 2013.

9. Lodhi IJ, Yin L, Jensen-Urstad APL, Funai K, Coleman T, Baird JH, El Ramahi MK, Razani B, Song H, Fu-Hsu F, Turk J, Semenkovich CF. Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity. Cell Metab. 16(2):189-201, 2012.

10. Funai K, Semenkovich CF. Skeletal muscle lipid flux: running water carries no poison. Am J Physiol Endo Metab. 301(2):E245-251, 2011.

11. Schweitzer GG, Castorena CM, Hamada T, Funai K, Arias EB, Cartee GD. The B2 receptor of bradykinin is not essential for the increase in glucose uptake by insulin-stimulated mouse skeletal muscle. Physiol Res. 60(3):511-519, 2011.

12. Funai K, Schweitzer GG, Castorena CM, Kanzaki M, Cartee GD. In vivo exercise followed by in vitro contraction additively elevates subsequent insulin-stimulated glucose transport by rat skeletal muscle. Am J Physiol Endo Metab. 298(5):E999-1010, 2010.

13. Cartee GD, Funai K. Exercise and insulin: Convergence or divergence at AS160 and TBC1D1? Exerc Sport Sci Rev. 37(4): 188-195, 2009.

14. Funai K, Schweitzer GG, Sharma N, Kanzaki M, Cartee GD. Increased AS160 phosphorylation, but not TBC1D1 phosphorylation, with increased post-exercise insulin sensitivity in rat skeletal muscle. Am J Physiol Endo Metab. 297(1):E242-251, 2009.

15. Funai K, Cartee GD. Inhibition of contraction-stimulated activation of AMP-activated protein kinase inhibits contraction-stimulated increases in glucose transport and PAS-TBC1D1 without altering PAS-AS160 in rat skeletal muscle. Diabetes. 58(5):1096-1104, 2009.

16. Blair DR, Funai K, Schweitzer GG, Cartee GD. A type II myosin ATPase inhibitor reduces contraction-stimulated glucose transport in rat skeletal muscle. Am J Physiol Endo Metab. 296(5):E993-1002, 2009.

17. Funai K, Cartee GD. Contraction-stimulated glucose transport in rat skeletal muscle is sustained despite reversal of increased PAS-phosphorylation of AS160 and TBC1D1. J Appl Physiol. 105(6):1788-1795, 2008.

18. Arias EB, Kim J, Funai K, Cartee GD. Prior exercise increases phosphorylation of Akt substrate of 160kDa (AS160) in rat skeletal muscle. Am J Physiol Endo Metab. 292(4):E1191-200, 2007.

19. Funai K, Parkington JD, Carambula S, Fielding RA. Age associated decrease in contraction-induced activation of downstream targets of Akt/mTOR signaling in skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 290(4):R1080-R1086, 2006.



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